Results Azithromycin reduced asthma exacerbations 1 07 per patient year 95 CI 0 85 1 29 compared with placebo 1 86 per patient year 1 54 2 18; incidence rate ratio IRR 0 59 95 CI 0 47 0 74; p Conclusions Adults with persistent symptomatic asthma experience fewer asthma exacerbations and improved quality of life when treated with oral azithromycin for 48 weeks cytotec over the The Hydrophile Lipophile Balance HLB number is an indication of the relative strength of the hydrophilic and hydrophobic portions of the molecule and can be used to characterize the relative affinity of surfactants for aqueous and organic phases